January 16, 2025
Apolipoprotein L1 gene (APOL1) variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD and the clinical association of A...
Rasheed A. Gbadegesin, Akinlolu Ojo
January 16, 2025
Chronic kidney disease (CKD) has a devastating effect on populations of African ancestry worldwide and disproportionately affects persons in West African countries,1 in whom CKD, once present, ofte...
Simone Sanna-Cherchi
January 16, 2025
Aortic-valve stenosis is an increasingly common clinical condition in the aging population. Population studies indicate a prevalence of up to 2.5% even among persons younger than 75 years of age, w...
Stefan Blankenberg
January 16, 2025
To the Editor: The review article by Guille and Sen (Oct. 24 issue)1 on physician burnout and depression offers valuable insights but overlooks nursing professionals, which limits our understanding...
January 16, 2025
A 21-year-old man with sickle cell disease was evaluated after loss of consciousness resulting in a fall. MRI of the head showed no clinically significant hemorrhage or evidence of restricted diffu...
Eric F. Shappell, David J. Lin
January 16, 2025
Physician shortages in the United States are projected to worsen, especially in rural areas. The authors argue that broad reforms, including changes in education and compensation, are needed.
Rochelle P. Walensky, Nicole C. McCann
January 16, 2025
CMS has taken steps to recognize the importance of primary care and the time and effort required for care teams to develop long-lasting, trusting relationships with patients.
Douglas B. Jacobs, Meena Seshamani
January 16, 2025
A 38-year-old woman with a history of disordered eating was found to have ground-glass opacities on a chest CT. Cytologic examination of bronchoalveolar-lavage fluid showed lipid-laden macrophages ...
Taichi Kaneko, Ryota Otoshi
January 16, 2025
To the Editor: Solomon et al. (Oct. 24 issue)1 found that among patients with heart failure and mildly reduced or preserved ejection fraction, finerenone resulted in a lower rate of a composite of ...
January 16, 2025
Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate admin...
Mark J. Bolland, Anne Horne
January 16, 2025
Several clinical and biologic methods are available to identify alcohol use disorder. Pharmacologic treatment is available, but it is underused.
Paul S. Haber
January 16, 2025
To the Editor: Turner et al. (Oct. 31 issue)1 report improved progression-free survival with the addition of inavolisib to the standard-care combination of palbociclib and fulvestrant as first-line...
