October 30, 2025
Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not been established.We randomly assigned participants 45 to 85 years of age...
Jeffrey N. Katz, Elena Losina
October 30, 2025
To the Editor: In the BATURA trial involving patients with mild asthma, LaForce and colleagues (July 10 issue)1 randomly assigned the patients to receive a fixed-dose combination of 180 ?g of albut...
October 30, 2025
Recognizing that half of eligible children are not enrolled in the supplementary nutrition program for women, infants, and children, two academic medical centers launched an automatic enrollment pr...
Lilianna Suarez, Rushina Cholera
October 30, 2025
A 56-year-old man was admitted to the hospital because of left lower abdominal pain and anemia. He had a 1-year history of recurrent diarrhea and an enterocolonic fistula. A diagnosis was made.
Bruce E. Sands, Dingani Nkosi
October 30, 2025
The race-adjusted estimated glomerular filtration rate reduced Black patients’ access to kidney transplants. NYC Health+Hospitals is studying the effect of a race-neutral algorithm.
Angelica Bocour, Leo G. Eisenstein
October 30, 2025
To the Editor: An Organ Procurement and Transplantation Network (OPTN) white paper challenged the ethics of normothermic regional perfusion mainly because it was not compatible with the “dead donor...
October 30, 2025
Approaches to early detection of cancer often seem contentious, but the big-picture view is actually one of remarkable consensus. All major guideline groups recommend the Papanicolaou smear, mammog...
Andrew Vickers
October 30, 2025
Somatic mutations in EGFR (epidermal growth factor receptor) account for approximately one third of lung cancer cases worldwide.1 A point mutation in exon 21 (L858R) or a short deletion in exon 19 ...
Anastasios Dimou, Aaron Mansfield
October 30, 2025
The European Randomized Study of Screening for Prostate Cancer (ERSPC) was initiated in 1993 to assess the effect of prostate-specific antigen (PSA) testing on prostate cancer mortality. Because de...
Monique J. Roobol, Anssi Auvinen
October 30, 2025
To the Editor: The CONFIDENCE trial, conducted by Agarwal et al. (Aug. 7 issue),1 showed that combination therapy with finerenone and empagliflozin led to a significantly greater reduction in the u...
October 30, 2025
A new FDA program is being promoted as a tool to facilitate the development and approval of therapies that are important for society. But it risks undermining regulatory innovation and trust in the...
Daniel Carpenter, Aaron S. Kesselheim
October 30, 2025
A 30-year-old man presented with recurrent, painful vesicles on his left lower eyelid. Clustered, umbilicated erosions and ulcers were found on an erythematous base on the medial aspect of the lowe...
