September 11, 2025
A 5-year-old boy with IgA vasculitis presented with scrotal swelling and pain and worsening of his leg rash. The physical examination showed purpura on the legs and swelling, erythema, and tenderne...
Sheri Pariha, Christian Hanna
September 11, 2025
Beta-blockers have been the initial treatment for symptomatic obstructive hypertrophic cardiomyopathy (HCM) despite limited evidence of their efficacy. Aficamten is a cardiac myosin inhibitor that ...
Pablo Garcia-Pavia, Michael A. Fifer
September 11, 2025
Recognizing doctors’ lack of confidence in caring for people with intellectual or developmental disabilities, a Stanford residency program and a local service organization created an introductory c...
Lauren Clarke, Christine Santiago
September 11, 2025
A 93-year-old woman was evaluated by her primary care physician because of dyspnea. She had a history of aortic stenosis and atrial fibrillation and flutter. A diagnosis was made.
Suzanne V. Arnold, Nathanael Tran
September 11, 2025
Unmet diaper need in low-income families affects children’s well-being, families’ financial constraints, and caregivers’ mental health. A Syracuse pediatric medical home is attempting to address th...
Winter Berry, Steven D. Blatt
September 11, 2025
To the Editor: In the SYMMETRY trial involving patients with metabolic dysfunction–associated steatohepatitis (MASH) with biopsy-confirmed compensated cirrhosis, Noureddin et al. (June 26 issue)1 c...
September 11, 2025
Hypertrophic cardiomyopathy (HCM) is a common, often inherited, and complex cardiac disease that can result in a high symptom burden. The principles of HCM management include familial cascade scree...
Amrut V. Ambardekar
September 11, 2025
A majority of U.S. Republicans support withholding federal funding from “ultraliberal” universities — but maintaining medical research funding. A national campaign could boost advocacy for such a c...
Robert J. Blendon, Natalie B. Le
September 11, 2025
In hypertrophic cardiomyopathy, thickened heart muscle often obstructs blood flow. Imaging aids in diagnosis, and treatments such as myosin inhibitors and defibrillators have improved the prognosis.
Eugene Braunwald
September 11, 2025
Despite high cancer-related mortality, health systems serving American Indian and Alaska Native populations offer only primary care. The University of Oklahoma is bridging the gap with oncology ser...
Amanda E. Janitz, Dorothy A. Rhoades
September 11, 2025
In patients with STEMI with cardiogenic shock, early mechanical support with a microaxial pump reduced the risk of death at 180 days, with the survival benefit persisting up to 10 years despite dev...
Jacob E. Møller, Christian Hassager
September 11, 2025
On September 27, 2024, Rwanda reported an outbreak of Marburg virus disease (MVD), after a cluster of cases of viral hemorrhagic fever was detected at two urban hospitals.We report key aspects of t...
