July 17, 2025
A 55-year-old man with metastatic squamous-cell lung cancer presented with a 6-week history of pain and swelling of the right great toe and the tip of the right middle finger.
Harriet O’Rourke, Mahesh Iddawela
July 17, 2025
To the Editor: In the API-CAT trial (April 10 issue),1 Mahé and colleagues confirm that a reduced dose of apixaban (2.5 mg twice daily) is noninferior to a full dose (5.0 mg) of the drug for preven...
July 17, 2025
An 86-year-old woman with a complex history that included multinodular goiter presented with neck swelling and dysphagia. A tender submandibular mass was present. A diagnosis was made.
Matthew L. Russell, Yin P. Hung
July 17, 2025
Prednisone is currently recommended as the first-line treatment for pulmonary sarcoidosis but is associated with many side effects. Methotrexate, which is recommended as a second-line treatment, ap...
Vivienne Kahlmann, Marlies S. Wijsenbeek
July 17, 2025
Allogeneic peripheral-blood stem-cell transplantation (SCT) from a matched related donor after myeloablative conditioning is the preferred curative treatment for patients with high-risk blood cance...
David J. Curtis, Geoffrey R. Hill
July 17, 2025
Sarcoidosis, a granulomatous disease that affects the lungs and other organs, has a variable course. Although spontaneous resolution of sarcoidosis occurs in some patients, half the patients with s...
Robert P. Baughman, Elyse E. Lower
July 17, 2025
A 60-year-old man with hypertension and bipolar disorder was incidentally found to have small cysts on his kidneys during MRI of the abdomen.
Cheng-Hung Liao, Kao-Lang Liu
July 17, 2025
Two patients with monoclonal anti-PF4 antibodies, thrombosis, and chronic thrombocytopenia also had first-trimester pregnancy losses, findings that suggest a possible link between these antibodies ...
Natalie R. Bavli, Anand Padmanabhan
July 17, 2025
Ondansetron improves outcomes when administered in emergency departments to children with acute gastroenteritis–associated vomiting. It is commonly prescribed at discharge to reduce symptoms, but e...
Stephen B. Freedman, Terry P. Klassen
July 17, 2025
AI mammography aids are being sold as additions to mammography screening, with direct-to-consumer marketing touting improved cancer-detection rates, despite a lack of evidence of clinical effective...
Benjamin Hyams, Rita F. Redberg
July 17, 2025
Gastric and gastroesophageal junction cancers remain a major global health challenge, with a high risk of recurrence despite surgery and perioperative chemotherapy. The standard perioperative regim...
Kohei Shitara
July 17, 2025
Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list t...
