August 15, 2024
A 58-year-old man presented with a 2-year history of eyelid lesions and several months of weight loss and fatigue. Scattered periorbital petechiae and purpura were noted, as well as coalescing, wax...
Miguel Mansilla Polo, Margarita Llavador-Ros
August 15, 2024
Brain–computer interfaces can enable communication for people with paralysis by transforming cortical activity associated with attempted speech into text on a computer screen. Communication with br...
Nicholas S. Card, David M. Brandman
August 15, 2024
A 12-year-old boy with autism complicated by developmental delay, selective eating, and toe walking was admitted to the hospital because of decreased vision in both eyes. A diagnosis was made.
Eric D. Gaier, Sarah M. Kadzielski
August 15, 2024
Patients with brain injury who are unresponsive to commands may perform cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). This phen...
Yelena G. Bodien, Nicholas D. Schiff
August 15, 2024
The author discusses the diagnosis and management of CKD of genetic origin in adults, focusing on single-gene variants that cause or confer a substantial risk of progressive CKD.
Asaf Vivante
August 15, 2024
A 70-year-old man with rheumatoid arthritis presented with painful, red lesions on the right side of his penis and scrotum and on his inner right thigh and a 1-day history of difficulty urinating.
Chengbei Bao, Chao Ji
August 15, 2024
Having adapted to her blindness and prosthetic leg, a passionate cyclist confronts the “chronic bonk” of cancer by aiming for the polka-dot jersey that symbolizes the strength to endure.
Charlotte Hayes
August 15, 2024
The durability of communication with the use of brain–computer interfaces in persons with progressive neurodegenerative disease has not been extensively examined. We report on 7 years of independen...
Mariska J. Vansteensel, Nick F. Ramsey
August 15, 2024
Osimertinib is a recommended treatment for advanced non–small-cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation and as adjuvant treatment for resected EGFR-mutated N...
Shun Lu, Suresh S. Ramalingam
August 15, 2024
Exactly 20 years ago, the precision-medicine revolution in lung cancer began with the discovery of sensitizing mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain,1,2 pr...
Natasha B. Leighl
August 15, 2024
In recent years, substantial progress has been made in developing brain-computer interfaces that could restore the ability of patients with neurodegenerative diseases and other conditions to commun...
August 15, 2024
Despite a groundswell of support, data on sexual orientation and gender identity still aren’t routinely collected or utilized in the U.S. health care system, which has implications for quality and ...
