January 9, 2025
New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ran...
Amanda J. Ullman, Robert S. Ware
January 9, 2025
An 84-year-old man was noted to have gray skin. On physical examination, diffuse gray pigmentation of the skin, nails, and sclera was seen. A skin biopsy revealed small, dark granules in sweat glands.
Tin Yan Lee, Wan Hang Lau
January 9, 2025
A 35-year-old woman was admitted at 8 weeks postpartum because of shortness of breath and edema in the legs. Proteinuria had developed at the end of the pregnancy. A diagnosis was made.
Jessica S. Tangren, Veronica E. Klepeis
January 9, 2025
Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation cl...
Nico Gagelmann, Nicolaus Kröger
January 9, 2025
Making integrated fracture liaison services a routine part of postfracture care could help reduce disparities in care — and may offer a useful model for the management of other chronic diseases.
Nicola Napoli, Douglas P. Kiel
January 9, 2025
The past two decades have witnessed a renaissance in the evaluation and treatment of patients with valvular heart disease, catalyzed by advances in surgical innovation, transcatheter techniques, an...
Patrick T. O’Gara
January 9, 2025
Heart failure with preserved ejection fraction is noted for symptoms of heart failure, LVEF of at least 50%, and cardiac or structural abnormalities. Treatment includes diuretics and SGLT2 inhibitors.
Antonio Cannata, Theresa A. McDonagh
January 9, 2025
This report describes a novel tickborne orthonairovirus species identified in patients presenting with an acute febrile illness in China.
Ming-Zhu Zhang, Wu-Chun Cao
January 9, 2025
This Double Take video discusses the differential diagnosis for a man presenting with persistent abdominal pain, fatigue, and anorexia with weight loss and reviews how it evolves with new clinical ...
Ann Cheung, Caren G. Solomon
January 9, 2025
In this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research being presented at the 2024 European Society of Cardiology annual meeting. . . .
Eric J. Rubin, Stephen Morrissey
January 9, 2025
A man with prostate cancer who was receiving androgen blockade had a substantial reduction in the frequency of hot flashes with the use of fezolinetant.
Kevin L. Lin, Anthony M. Joshua
January 9, 2025
Persistent chylomicronemia is a genetic recessive disorder that is classically caused by familial chylomicronemia syndrome (FCS), but it also has multifactorial causes. The disorder is associated w...
