July 10, 2025
To the Editor: In the Clinical Practice article by Krist and Bradley (May 1 issue),1 they mention that “any alcohol use can adversely affect health.” Blanket messages may oversimplify complex evide...
July 10, 2025
As-needed use of albuterol–budesonide has been shown to result in a significantly lower risk of severe asthma exacerbation than as-needed use of albuterol alone among patients with moderate-to-seve...
Craig LaForce, Leonard B. Bacharier
July 10, 2025
To the Editor: The results of the OPTION trial (Comparison of Anticoagulation with Left Atrial Appendage Closure after Atrial Fibrillation Ablation), reported by Wazni et al. (April 3 issue),1 show...
July 10, 2025
A 69-year-old man with a history of diffuse large B-cell lymphoma presented to the hospital with headache and ataxia. MRI showed diffuse bilateral hyperintensities on T2-weighted FLAIR images. A di...
Arun Venkatesan, Erik H. Klontz
July 10, 2025
Cardiovascular diseases, principally ischemic heart disease and stroke, have consistently been the leading cause of death worldwide since 1990 and accounted for 19.8 million deaths in 2022 alone.1 ...
George A. Mensah
July 10, 2025
The financial assistance policies of some U.S. hospitals now define medical necessity much more restrictively than it has conventionally been understood, as covering only services that are urgently...
Mark A. Hall, Judith Garber
July 10, 2025
During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.
David Helekal, Yonatan H. Grad
July 10, 2025
Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular dise...
The Global Cardiovascular Risk Consortium
July 10, 2025
A 77-year-old woman presented with a 2-day history of abdominal pain, nausea, and vomiting. CT of the abdomen revealed herniation of a loop of ileum that was inferior to the inguinal ligament and l...
Pratyaksha Rana, Hit Jivani
July 10, 2025
The safety and efficacy of treatment with intravenous tenecteplase before endovascular thrombectomy in patients with acute ischemic stroke due to large-vessel occlusion remain uncertain.In this ope...
Zhongming Qiu, Qingwu Yang
July 10, 2025
This review discusses the features of oligoarticular, polyarticular, systemic, and psoriatic JIA and enthesitis-related arthritis, as well as advances in treatment for these conditions.
Christy I. Sandborg, Yukiko Kimura
July 10, 2025
As her patients near the end of life, an infectious disease physician who knows their stories sometimes needs to step out of her proverbial lane to help them assess and achieve their goals of care.
